Oxidation to carboxylic acids [H2CrO4 + others]
Oxidation to carboxylic acids [H2CrO4 + others] Definition:
Primary alcohols treated with chromic acid will be converted to carboxylic acid.
Oxidation to carboxylic acids [H2CrO4 + others] Explained:
The outcome of an oxidation process depends on the starting alcohol. If we have primary alcohol which has two hydrogen atoms at the α position, it can be oxidized twice. The first oxidation yields an aldehyde, and further oxidation of this aldehyde gives the carboxylic acid. Secondary alcohols only have one proton at the α position so they can only be oxidized once, forming a ketone that cannot be oxidized further. Tertiary alcohols do not undergo oxidation because they do not have any protons at the α position.
Chromic acid (H2CrO4) is mainly used to produce a carboxylic acid. It can be formed either from chromium trioxide (CrO3) or from sodium dichromate (Na2Cr2O7) in aqueous acidic solution.
This mechanism consists of two main steps:
STEP 2: E2 process form a carbon-oxygen π bond
Here obtained an aldehyde which is difficult to isolate. This reaction goes further to carboxylic acid by protonation.