N-Glycoside

N-Glycoside Definition:

The product obtained when a monosaccharide is treated with an amine in the presence of an acid catalyst.

N-Glycoside Explained:

N-glycoside and steroids from Aristolochia indica, N-glycosidase that hydrolyzes the adenine ring from a specific adenosine of rRNA. Formycin monophosphate (FMP) and adenyl(3′ → 5′)guanosine (ApG) were bound to ricin A-chain and their structures elucidated by X-ray crystallography. The formycin ring stacks between tyrosines 80 and 123 and at least four hydrogen bonds are made to the adenine moiety.