Thiol oxidation to disulfides Thiol oxidation to disulfides Definition: When thiols treated with an oxidizing agent such as iodine or molecular oxygen, thiols can be converted to disulfides. Thiol oxidizing to disulfides Explained: Thiols easily undergo oxidation…
Thiol formation [HS(–)] Thiol formation (HS‾) Definition: Alkyl halides (or tosylate) will react with the hydrosulfide anion (HS‾) to give thiols. Thiol formation (HS‾) Explained: In a concerted process, nucleophilic attack and loss of a…
Thioether formation RS- Thioether formation (RS‾) Definition: Alkyl halides (or tosylates) will react with thiolate anions to form sulfides (or thioether) in an SN2 reaction. Thioether formation (RS‾) Explained: Nucleophilic substitution at an sp³ hybridized carbon involves…